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| What is Growth Factor |
Growth Factors are proteins that bind to their own receptors on cell surface, with the primary result of
activating cell proliferation and/or differentiation.
Not only as strong mitogens, growth factors are regulating the expressions of ECMs(Extra Cellular Matrix) like
collagen, elastin and laminin etc. |
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| Superiority of Growth Factors |
- Competitive price based on exclusive mass production technology
- High efficacy and stability by nano-encapsulation technology
- High purity by sophisticated production facility and technical superiority |
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| ¢º Manufacturing Process of Growth Factors |
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| What is Biomimetic Peptides |
Caregen has developed biomimetic peptides since 2002 based on various and broad growth factor studies.
Caregen¡¯s commercialized peptides are synthetic agonists of naturally-occurring growth factors and are
completely mimic the action of the parental molecule. Those biomimetic peptides can provide clinical
benefits similar to recombinant growth factors, reduced costs, and greater chemical stability.
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| Comparative Advantage of Biomimetic Peptides |
- Sustainable new biomimetic peptides development
- Competitive price based on mass production technology
- High efficacy and stability by nano-encapsulation technology
- High purity by sophisticated production facility and technical superiority |
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| ¢º Manufacturing Process of Growth Factors |
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| Nano-encapsulation Technology |
Caregen nano-encapsulation technology improves penetration efficiency of active ingredients into skin.
In addition, the molecules are protected from endogenous proteases due to nano-capsulation. |
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| Advantages of Nano-encapsulation |
- High stability by double layered structure
- High homogeneity: average diameter of particle is 140 nm and over 80% particles are below 100 nm size.
- Efficient Delivery of therapeutic cosmetic components into dermal layer. |
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| Penetration Test for Nano-encapsulation |
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Topical Cream Treatment
FITC-labeled growth factors and biomimetic peptides were nano-encapsulated. |
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Stem cell is a type of blast cell, which can differentiate to various adult cell including
skin cell and hair cell. Caregen has focused on stem cell differentiation to skin Keratinocytes. |
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